The principle and application of high pressure homogenizer for cell crushing

Source:Changzhou Chaoli Homogenizer Factory Release time:2023-08-23 14:00:36 Author:651

The high-pressure homogenizer uses high pressure to make the cell suspension pass through the needle valve. Due to the sudden decompression and high-speed impact on the impact ring, the cells are broken. When the cell suspension is ejected from the needle valve in the high-pressure chamber, the speed is as high as several hundred meters per second. The slurry jetted out at high speed hits the stationary impingement ring and is forced to change direction and flow out of the outlet pipe. During this series of high-speed movements, the cells experienced shearing, collision and changes from high pressure to normal pressure, resulting in cell fragmentation.
High-pressure homogenizers are widely used in biomedicine, biopharmaceutical, food industry, environmental protection and other fields. In the cell crushing industry, high-pressure homogenizers are widely used in:
1. Cell crushing: The high-pressure homogenizer can crush cells into components such as cell membrane, cytoplasm, and nucleus, which is beneficial to research in the fields of cytology and molecular biology.
2. Protein extraction: The high-pressure homogenizer can extract protein, which is beneficial to the research and development of biomedicine, biopharmaceutical and other fields.
3. DNA/RNA extraction: The high-pressure homogenizer can extract DNA/RNA, which is beneficial to the research and development of molecular biology and other fields.
4. Drug preparation: The high-pressure homogenizer can be used for drug preparation and crushing, mixing and other processes in the production process, which is conducive to improving the quality and efficiency of drugs.
High-pressure homogenizers have the following advantages in the cell crushing industry:
1. Efficient: The high-pressure homogenizer can break the sample into nanometer level in a short time, which improves the research and production efficiency.
2. High precision: The high-pressure homogenizer can control the pressure, time, speed and other parameters of the crushing process, making the crushing results more accurate and controllable.
3. Wide range of application: The high-pressure homogenizer can crush different types of cells, organelles, molecules and other samples, and has a wide range of application.
4. Simple operation: The high-pressure homogenizer is easy to operate and does not require special skills and experience.

In conclusion, the high-pressure homogenizer has a wide range of applications and advantages in the cell crushing industry, providing strong support for research and production.